NOT KNOWN FACTUAL STATEMENTS ABOUT CIANURO IN ITALIA

Hepatic Impairment Immediately after oral administration of an individual four mg dose (two mg hydromorphone instant-release tablets), suggest publicity to hydromorphone (Cmax and AUC∞) is improved four-fold in sufferers with average (Kid-Pugh Group B) hepatic impairment in contrast with topics with usual hepatic perform. Resulting from increased